Rabbit Anti-R51A1/RAD51AP1 Polyclonal Antibody
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产品编号
PAV3232
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别名
RAD51 associated protein 1, PIR51
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | RAD51 associated protein 1, PIR51 |
| Catalog Number | PAV3232 |
| Product Description | Rabbit polyclonal antibody raised against human RAD51AP1 (RAD51-associated protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RAD51AP1 |
| Species | Human, Mouse, |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | DNA损伤修复 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables DNA binding activity and RNA binding activity. Involved in DNA repair; cellular response to ionizing radiation; and positive regulation of DNA recombination. Located in chromatin and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human RAD51AP1 protein (UniProt: Q96B01) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10635 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, |
| Predicted Molecular Weight | ≈38.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 38.5 kDa |
| Cross-reactivity | Human, Mouse, |
| Uniprot ID | Q96B01 |
| Note | Gene ID: 10635; UniProt: Q96B01; Chromosome: 12p13.32; Predicted MW: 38.5 kDa |
| Function | Structure-specific DNA-binding protein involved in DNA repair by promoting RAD51-mediated homologous recombination. Acts by stimulating D-Loop formation by RAD51: specifically enhances joint molecule formation through its structure-specific DNA interaction and its interaction with RAD51. Binds single-stranded DNA (ssDNA), double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures: has a strong preference for branched-DNA structures that are obligatory intermediates during joint molecule formation. Cooperates with WDR48/UAF1 to stimulate RAD51-mediated homologous recombination: both WDR48/UAF1 and RAD51AP1 have coordinated role in DNA-binding during homologous recombination and DNA repair. WDR48/UAF1 and RAD51AP1 also have a coordinated role in DNA-binding to promote USP1-mediated deubiquitination of FANCD2. Also involved in meiosis by promoting DMC1-mediated homologous meiotic recombination. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RAD51AP1 Polyclonal Antibody |
| Target | RAD51AP1 |
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