Rabbit Anti-TTC18/CFAP70 Polyclonal Antibody
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产品编号
PAV4174
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别名
cilia and flagella associated protein 70, SPGF41, TTC18
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | cilia and flagella associated protein 70, SPGF41, TTC18 |
| Catalog Number | PAV4174 |
| Product Description | Rabbit polyclonal antibody raised against human CFAP70 (Cilia- and flagella-associated protein 70). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | CFAP70 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to be involved in cilium assembly and cilium movement. Predicted to act upstream of or within several processes, including maintenance of cell number; single fertilization; and spermatid development. Located in ciliary basal body and sperm flagellum. Part of outer dynein arm. Implicated in spermatogenic failure 41. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human CFAP70 protein (UniProt: Q5T0N1) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 118491 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈125.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 125.7 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q5T0N1 |
| Note | Gene ID: 118491; UniProt: Q5T0N1; Chromosome: 10q22.2; Predicted MW: 125.7 kDa |
| Function | Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length. Essential for the assembly of the sperm flagellum and the correct shaping of the sperm head, during spermiogenesis.Contributes in part to flagellar biogenesis by stabilizing QRICH2, promoting the cytoplasmic preassembly of CFAP61 and CFAP91, and regulating the manchette localization of axoneme-associated proteins such as IFT88, DNAI1 and CFAP61. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human CFAP70 Polyclonal Antibody |
| Target | CFAP70 |
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