首页
>>
产品中心
>>
抗体产品
>>
一抗
>>
结构蛋白与细胞骨架
>>
细胞骨架
>
Rabbit Anti-TIAF1 Polyclonal Antibody
Rabbit Anti-TIAF1 Polyclonal Antibody

Rabbit Anti-TIAF1 Polyclonal Antibody

产品编号

PAV4024

别名

myosin XVIIIA, MAJN, MYSPDZ, SP-R210, SPR210, TIAF1

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasmyosin XVIIIA, MAJN, MYSPDZ, SP-R210, SPR210, TIAF1
Catalog NumberPAV4024
Product DescriptionRabbit polyclonal antibody raised against human MYO18A (Unconventional myosin-XVIIIa). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NameMYO18A
SpeciesHuman
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family细胞骨架
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe protein encoded by this gene can bind GOLPH3, linking the Golgi to the cytoskeleton and influencing Golgi membrane trafficking. The encoded protein is also part of a complex that assembles lamellar actomyosin bundles and may be required for cell migration. [provided by RefSeq, Oct 2016]
ImmunogenThis antibody was raised against from part region of human MYO18A protein (UniProt: Q92614)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID399687
TagUnconjugated
Cross-reactivityHuman
Predicted Molecular Weight≈233.1 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight233.1 kDa
Cross-reactivityHuman
Uniprot IDQ92614
NoteGene ID: 399687; UniProt: Q92614; Chromosome: 17q11.2; Predicted MW: 233.1 kDa
FunctionMay link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking. Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages. Strongly enhances natural killer cell cytotoxicity.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human MYO18A Polyclonal Antibody
TargetMYO18A

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价