Rabbit Anti-TDIF1/DNTTIP1 Polyclonal Antibody
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产品编号
PAV3993
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别名
deoxynucleotidyltransferase terminal interacting protein 1, C20orf167, Tdif1, dJ447F3.4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | deoxynucleotidyltransferase terminal interacting protein 1, C20orf167, Tdif1, dJ447F3.4 |
| Catalog Number | PAV3993 |
| Product Description | Rabbit polyclonal antibody raised against human DNTTIP1 (Deoxynucleotidyltransferase terminal-interacting protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | DNTTIP1 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008] |
| Immunogen | This antibody was raised against from part region of human DNTTIP1 protein (UniProt: Q9H147) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 116092 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈37.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 37.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9H147 |
| Note | Gene ID: 116092; UniProt: Q9H147; Chromosome: 20q13.12; Predicted MW: 37.0 kDa |
| Function | Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human DNTTIP1 Polyclonal Antibody |
| Target | DNTTIP1 |
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