Rabbit Anti-MTNB/APIP Polyclonal Antibody
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产品编号
PAV2384
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别名
APAF1 interacting protein, APIP2, CGI-29, CGI29, MMRP19, hAPIP
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | APAF1 interacting protein, APIP2, CGI-29, CGI29, MMRP19, hAPIP |
| Catalog Number | PAV2384 |
| Product Description | Rabbit polyclonal antibody raised against human APIP (Methylthioribulose-1-phosphate dehydratase). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | APIP |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in several processes, including obsolete L-methionine salvage from methylthioadenosine; protein homotetramerization; and pyroptotic inflammatory response. Located in cytoplasm. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human APIP protein (UniProt: Q96GX9) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 51074 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈27.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 27.1 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96GX9 |
| Note | Gene ID: 51074; UniProt: Q96GX9; Chromosome: 11p13; Predicted MW: 27.1 kDa |
| Function | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human APIP Polyclonal Antibody |
| Target | APIP |
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