Rabbit Anti-MCF2L Polyclonal Antibody
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产品编号
PAV2264
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别名
MCF.2 cell line derived transforming sequence like, ARHGEF14, DBS, OST
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MCF.2 cell line derived transforming sequence like, ARHGEF14, DBS, OST |
| Catalog Number | PAV2264 |
| Product Description | Rabbit polyclonal antibody raised against human MCF2L (Guanine nucleotide exchange factor DBS). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MCF2L |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| Immunogen | This antibody was raised against from part region of human MCF2L protein (UniProt: O15068) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 23263 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈128.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 128.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | O15068 |
| Note | Gene ID: 23263; UniProt: O15068; Chromosome: 13q34; Predicted MW: 128.1 kDa |
| Function | Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways (By similarity). Seems to lack activity with RAC1. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.; FUNCTION: [Isoform 3]: Does not catalyze guanine nucleotide exchange on CDC42. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MCF2L Polyclonal Antibody |
| Target | MCF2L |
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