Rabbit Anti-MAP1B Polyclonal Antibody
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产品编号
PAV2239
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别名
microtubule associated protein 1B, DFNA83, FUTSCH, MAP5, PPP1R102, PVNH9
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | microtubule associated protein 1B, DFNA83, FUTSCH, MAP5, PPP1R102, PVNH9 |
| Catalog Number | PAV2239 |
| Product Description | Rabbit polyclonal antibody raised against human MAP1B (Microtubule-associated protein 1B). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: IHC-p. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MAP1B |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞骨架 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human MAP1B protein (UniProt: P46821) |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-200 |
| Gene ID | 4131 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈270.6 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 270.6 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P46821 |
| Note | Gene ID: 4131; UniProt: P46821; Chromosome: 5q13.2; Predicted MW: 270.6 kDa |
| Function | Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B is required for proper microtubule dynamics and plays a role in the cytoskeletal changes that accompany neuronal differentiation and neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MAP1B Polyclonal Antibody |
| Target | MAP1B |
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