Rabbit Anti-TR13C/TNFRSF13C Polyclonal Antibody
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产品编号
PAV4112
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别名
TNF receptor superfamily member 13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
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目录价格
InquiryRMB
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规格
- 100ul
| Alias | TNF receptor superfamily member 13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin |
| Catalog Number | PAV4112 |
| Product Description | Rabbit polyclonal antibody raised against human TNFRSF13C (Tumor necrosis factor receptor superfamily member 13C). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TNFRSF13C |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TNFRSF13C protein (UniProt: Q96RJ3) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 115650 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈18.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 18.9 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q96RJ3 |
| Note | Gene ID: 115650; UniProt: Q96RJ3; Chromosome: 22q13.2; Predicted MW: 18.9 kDa |
| Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TNFRSF13C Polyclonal Antibody |
| Target | TNFRSF13C |
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