Rabbit Anti-TNR8/TNFRSF8 Polyclonal Antibody
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产品编号
PAV4094
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别名
TNF receptor superfamily member 8, CD30, D1S166E, Ki-1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TNF receptor superfamily member 8, CD30, D1S166E, Ki-1 |
| Catalog Number | PAV4094 |
| Product Description | Rabbit polyclonal antibody raised against human TNFRSF8 (Tumor necrosis factor receptor superfamily member 8). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, IHC-p, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TNFRSF8 |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TNFRSF8 protein (UniProt: P28908) |
| Application | WB, IHC-p, ELISA |
| Recommended Dilution | WB 1:500-2000 IHC-p 1:50-200 ELISA 1:5000-20000 |
| Gene ID | 943 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈63.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 63.7 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P28908 |
| Note | Gene ID: 943; UniProt: P28908; Chromosome: 1p36.22; Predicted MW: 63.7 kDa |
| Function | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TNFRSF8 Polyclonal Antibody |
| Target | TNFRSF8 |
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