Rabbit Anti-TNR18/TNFRSF18 Polyclonal Antibody
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产品编号
PAV4090
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别名
TNF receptor superfamily member 18, AITR, CD357, ENERGEN, GITR, GITR-D
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TNF receptor superfamily member 18, AITR, CD357, ENERGEN, GITR, GITR-D |
| Catalog Number | PAV4090 |
| Product Description | Rabbit polyclonal antibody raised against human TNFRSF18 (Tumor necrosis factor receptor superfamily member 18). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TNFRSF18 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
| Immunogen | This antibody was raised against from part region of human TNFRSF18 protein (UniProt: Q9Y5U5) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8784 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈26.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 26.0 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9Y5U5 |
| Note | Gene ID: 8784; UniProt: Q9Y5U5; Chromosome: 1p36.33; Predicted MW: 26.0 kDa |
| Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TNFRSF18 Polyclonal Antibody |
| Target | TNFRSF18 |
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