Rabbit Anti-TNF18/TNFSF18 Polyclonal Antibody
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产品编号
PAV4079
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别名
TNF superfamily member 18, AITRL, GITRL, TL6, TNLG2A, hGITRL
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | TNF superfamily member 18, AITRL, GITRL, TL6, TNLG2A, hGITRL |
| Catalog Number | PAV4079 |
| Product Description | Rabbit polyclonal antibody raised against human TNFSF18 (Tumor necrosis factor ligand superfamily member 18). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TNFSF18 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TNFSF18 protein (UniProt: Q9UNG2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 8995 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈20.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 20.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9UNG2 |
| Note | Gene ID: 8995; UniProt: Q9UNG2; Chromosome: 1q25.1; Predicted MW: 20.3 kDa |
| Function | Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TNFSF18 Polyclonal Antibody |
| Target | TNFSF18 |
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