Rabbit Anti-OSGI1/OSGIN1 Polyclonal Antibody
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产品编号
PAV2869
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别名
oxidative stress induced growth inhibitor 1, BDGI, OKL38
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | oxidative stress induced growth inhibitor 1, BDGI, OKL38 |
| Catalog Number | PAV2869 |
| Product Description | Rabbit polyclonal antibody raised against human OSGIN1 (Oxidative stress-induced growth inhibitor 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | OSGIN1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011] |
| Immunogen | This antibody was raised against from part region of human OSGIN1 protein (UniProt: Q9UJX0) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 29948 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈52.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 52.0 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9UJX0 |
| Note | Gene ID: 29948; UniProt: Q9UJX0; Chromosome: 16q23.3; Predicted MW: 52.0 kDa |
| Function | Monooxygenase catalytic activity. Involved in regulation of cytokinesis; promotes RHOA activity, probably acting locally at the midbody in late cytokinesis. Monooxygenase activity is involved in stabilizing transient structures between daughter cells, termed intercellular bridges, before abscission. Regulates differentiation and proliferation through the regulation of cell death. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human OSGIN1 Polyclonal Antibody |
| Target | OSGIN1 |
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