Rabbit Anti-NFAM1 Polyclonal Antibody
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产品编号
PAV2510
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别名
NFAT activating protein with ITAM motif 1, CNAIP
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NFAT activating protein with ITAM motif 1, CNAIP |
| Catalog Number | PAV2510 |
| Product Description | Rabbit polyclonal antibody raised against human NFAM1 (NFAT activation molecule 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NFAM1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a type I membrane receptor that activates cytokine gene promoters such as the IL-13 and TNF-alpha promoters. The encoded protein contains an immunoreceptor tyrosine-based activation motif (ITAM) and is thought to regulate the signaling and development of B-cells. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human NFAM1 protein (UniProt: Q8NET5) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 150372 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈29.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 29.7 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q8NET5 |
| Note | Gene ID: 150372; UniProt: Q8NET5; Chromosome: 22q13.2; Predicted MW: 29.7 kDa |
| Function | May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NFAM1 Polyclonal Antibody |
| Target | NFAM1 |
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