Rabbit Anti-MT1A Polyclonal Antibody
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产品编号
PAV2379
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别名
metallothionein 1A, MT-1A, MT-IA, MT1, MT1S, MTC
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | metallothionein 1A, MT-1A, MT-IA, MT1, MT1S, MTC |
| Catalog Number | PAV2379 |
| Product Description | Rabbit polyclonal antibody raised against human MT1A (Metallothionein-1A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: IHC-p. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MT1A |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞因子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017] |
| Immunogen | This antibody was raised against from part region of human MT1A protein (UniProt: P04731) |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-200 |
| Gene ID | 4489 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈6.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 6.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | P04731 |
| Note | Gene ID: 4489; UniProt: P04731; Chromosome: 16q13; Predicted MW: 6.1 kDa |
| Function | Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MT1A Polyclonal Antibody |
| Target | MT1A |
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