Rabbit Anti-SPY1/SPDYA Polyclonal Antibody
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产品编号
PAV3809
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别名
speedy/RINGO cell cycle regulator family member A, RINGO3, RINGOA, SPDY1, SPY1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | speedy/RINGO cell cycle regulator family member A, RINGO3, RINGOA, SPDY1, SPY1 |
| Catalog Number | PAV3809 |
| Product Description | Rabbit polyclonal antibody raised against human SPDYA (Speedy protein A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SPDYA |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞周期 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Enables protein kinase activator activity and protein kinase binding activity. Involved in DNA damage response; G1/S transition of mitotic cell cycle; and positive regulation of cell population proliferation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human SPDYA protein (UniProt: Q5MJ70) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 245711 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈36.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 36.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q5MJ70 |
| Note | Gene ID: 245711; UniProt: Q5MJ70; Chromosome: 2p23.2; Predicted MW: 36.5 kDa |
| Function | Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2. Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Mediates cell survival during the DNA damage process through activation of CDK2. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SPDYA Polyclonal Antibody |
| Target | SPDYA |
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