Rabbit Anti-PCNT Polyclonal Antibody
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产品编号
PAV2969
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别名
pericentrin, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | pericentrin, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4 |
| Catalog Number | PAV2969 |
| Product Description | Rabbit polyclonal antibody raised against human PCNT (Pericentrin). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: IHC-p. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PCNT |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞周期 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Immunogen | This antibody was raised against from part region of human PCNT protein (UniProt: O95613) |
| Application | IHC-p |
| Recommended Dilution | IHC-p 1:50-200 |
| Gene ID | 5116 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈378.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 378.0 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | O95613 |
| Note | Gene ID: 5116; UniProt: O95613; Chromosome: 21q22.3; Predicted MW: 378.0 kDa |
| Function | Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PCNT Polyclonal Antibody |
| Target | PCNT |
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