Rabbit Anti-NUF2 Polyclonal Antibody
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产品编号
PAV2641
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别名
NUF2 component of NDC80 kinetochore complex, CDCA1, CT106, NUF2R
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | NUF2 component of NDC80 kinetochore complex, CDCA1, CT106, NUF2R |
| Catalog Number | PAV2641 |
| Product Description | Rabbit polyclonal antibody raised against human NUF2 (Kinetochore protein Nuf2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | NUF2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞周期 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human NUF2 protein (UniProt: Q9BZD4) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 83540 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈54.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 54.3 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q9BZD4 |
| Note | Gene ID: 83540; UniProt: Q9BZD4; Chromosome: 1q23.3; Predicted MW: 54.3 kDa |
| Function | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human NUF2 Polyclonal Antibody |
| Target | NUF2 |
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