Rabbit Anti-SIG11/SIGLEC11 Polyclonal Antibody

产品编号

PAV3678

别名

sialic acid binding Ig like lectin 11

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	sialic acid binding Ig like lectin 11
Catalog Number	PAV3678
Product Description	Rabbit polyclonal antibody raised against human SIGLEC11 (Sialic acid-binding Ig-like lectin 11). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	SIGLEC11
Species	Human
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	细胞黏附
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Immunogen	This antibody was raised against from part region of human SIGLEC11 protein (UniProt: Q96RL6)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	114132
Tag	Unconjugated
Cross-reactivity	Human
Predicted Molecular Weight	≈75.8 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	75.8 kDa
Cross-reactivity	Human
Uniprot ID	Q96RL6
Note	Gene ID: 114132; UniProt: Q96RL6; Chromosome: 19q13.33; Predicted MW: 75.8 kDa
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,8-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human SIGLEC11 Polyclonal Antibody
Target	SIGLEC11