Rabbit Anti-SIAL/IBSP Polyclonal Antibody
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产品编号
PAV3676
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别名
integrin binding sialoprotein, BNSP, BSP, BSP II, BSP-II, SP-II
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | integrin binding sialoprotein, BNSP, BSP, BSP II, BSP-II, SP-II |
| Catalog Number | PAV3676 |
| Product Description | Rabbit polyclonal antibody raised against human IBSP (Integrin-binding sialoprotein). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | IBSP |
| Species | Human, Rat, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞黏附 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human IBSP protein (UniProt: P21815) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 3381 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Rat, Mouse |
| Predicted Molecular Weight | ≈35.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 35.1 kDa |
| Cross-reactivity | Human, Rat, Mouse |
| Uniprot ID | P21815 |
| Note | Gene ID: 3381; UniProt: P21815; Chromosome: 4q22.1; Predicted MW: 35.1 kDa |
| Function | Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human IBSP Polyclonal Antibody |
| Target | IBSP |
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