Rabbit Anti-PCDGD/PCDHGB1 Polyclonal Antibody
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产品编号
PAV2963
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别名
protocadherin gamma subfamily B, 1, PCDH-GAMMA-B1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protocadherin gamma subfamily B, 1, PCDH-GAMMA-B1 |
| Catalog Number | PAV2963 |
| Product Description | Rabbit polyclonal antibody raised against human PCDHGB1 (Protocadherin gamma-B1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PCDHGB1 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞黏附 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PCDHGB1 protein (UniProt: Q9Y5G3) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 56104 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈100.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 100.4 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9Y5G3 |
| Note | Gene ID: 56104; UniProt: Q9Y5G3; Chromosome: 5q31.3; Predicted MW: 100.4 kDa |
| Function | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PCDHGB1 Polyclonal Antibody |
| Target | PCDHGB1 |
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