Rabbit Anti-PCDA8/PCDHA8 Polyclonal Antibody
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产品编号
PAV2955
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别名
protocadherin alpha 8, PCDH-ALPHA8
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | protocadherin alpha 8, PCDH-ALPHA8 |
| Catalog Number | PAV2955 |
| Product Description | Rabbit polyclonal antibody raised against human PCDHA8 (Protocadherin alpha-8). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PCDHA8 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 细胞黏附 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human PCDHA8 protein (UniProt: Q9Y5H6) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 56140 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈103.1 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 103.1 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9Y5H6 |
| Note | Gene ID: 56140; UniProt: Q9Y5H6; Chromosome: 5q31.3; Predicted MW: 103.1 kDa |
| Function | Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PCDHA8 Polyclonal Antibody |
| Target | PCDHA8 |
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