Rabbit Anti-UB2E3/UBE2E3 Polyclonal Antibody
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产品编号
PAV4205
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别名
ubiquitin conjugating enzyme E2 E3, UBCH9, UbcM2
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | ubiquitin conjugating enzyme E2 E3, UBCH9, UbcM2 |
| Catalog Number | PAV4205 |
| Product Description | Rabbit polyclonal antibody raised against human UBE2E3 (Ubiquitin-conjugating enzyme E2 E3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | UBE2E3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2013] |
| Immunogen | This antibody was raised against from part region of human UBE2E3 protein (UniProt: Q969T4) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 10477 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈22.9 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 22.9 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q969T4 |
| Note | Gene ID: 10477; UniProt: Q969T4; Chromosome: 2q31.3; Predicted MW: 22.9 kDa |
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human UBE2E3 Polyclonal Antibody |
| Target | UBE2E3 |
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