Rabbit Anti-TRI31/TRIM31 Polyclonal Antibody
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产品编号
PAV4120
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别名
tripartite motif containing 31, C6orf13, HCG1, HCGI, RNF
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | tripartite motif containing 31, C6orf13, HCG1, HCGI, RNF |
| Catalog Number | PAV4120 |
| Product Description | Rabbit polyclonal antibody raised against human TRIM31 (E3 ubiquitin-protein ligase TRIM31). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TRIM31 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| Immunogen | This antibody was raised against from part region of human TRIM31 protein (UniProt: Q9BZY9) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 11074 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈48.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 48.2 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q9BZY9 |
| Note | Gene ID: 11074; UniProt: Q9BZY9; Chromosome: 6p22.1; Predicted MW: 48.2 kDa |
| Function | E3 ubiquitin-protein ligase that acts as a regulator of antiviral immune response and inflammation by mediating ubiquitination of substrates. Acts as a regulator of innate immune defense against viruses by mediating 'Lys-63'-linked ubiquitination of MAVS, promoting MAVS polymerization and formation of three-stranded helical filaments on mitochondria. Acts as a negative regulator of the NLRP3 inflammasome by catalyzing 'Lys-48'-linked ubiquitination of NLRP3, leading to its degradation. Regulator of Src-induced anchorage independent cell growth (By similarity). |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TRIM31 Polyclonal Antibody |
| Target | TRIM31 |
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