Rabbit Anti-SNUT2/USP39 Polyclonal Antibody
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产品编号
PAV3737
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别名
ubiquitin specific peptidase 39, 65K, CGI-21, HSPC332, SAD1, SNRNP65
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | ubiquitin specific peptidase 39, 65K, CGI-21, HSPC332, SAD1, SNRNP65 |
| Catalog Number | PAV3737 |
| Product Description | Rabbit polyclonal antibody raised against human USP39 (Ubiquitin carboxyl-terminal hydrolase 39). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | USP39 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable cysteine-type deubiquitinase activity and zinc ion binding activity. Involved in spliceosomal complex assembly. Located in nucleoplasm. Part of U4/U6 x U5 tri-snRNP complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human USP39 protein (UniProt: Q53GS9) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 10713 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈65.4 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 65.4 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q53GS9 |
| Note | Gene ID: 10713; UniProt: Q53GS9; Chromosome: 2p11.2; Predicted MW: 65.4 kDa |
| Function | Deubiquitinating enzyme that plays a role in many cellular processes including cellular antiviral response, epithelial morphogenesis, DNA repair or B-cell development. Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome. Specifically regulates immunoglobulin gene rearrangement in a spliceosome-dependent manner, which involves modulating chromatin interactions at the Igh locus and therefore plays an essential role in B-cell development (By similarity). Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint. Regulates apoptosis and G2/M cell cycle checkpoint in response to DNA damage by deubiquitinating and stabilizing CHK2. Also plays an important role in DNA repair by controlling the recruitment of XRCC4/LIG4 to DNA double-strand breaks for non-homologous end-joining repair. Participates in antiviral activity by affecting the type I IFN signaling by stabilizing STAT1 and decreasing its 'Lys-6'-linked ubiquitination. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human USP39 Polyclonal Antibody |
| Target | USP39 |
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