Rabbit Anti-SIAH3 Polyclonal Antibody
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产品编号
PAV3675
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别名
siah E3 ubiquitin protein ligase family member 3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | siah E3 ubiquitin protein ligase family member 3 |
| Catalog Number | PAV3675 |
| Product Description | Rabbit polyclonal antibody raised against human SIAH3 (Seven in absentia homolog 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SIAH3 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Involved in obsolete negative regulation of protein targeting to mitochondrion and regulation of protein stability. Located in mitochondrion. [provided by Alliance of Genome Resources, Jun 2026] |
| Immunogen | This antibody was raised against from part region of human SIAH3 protein (UniProt: Q8IW03) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 283514 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈30.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 30.7 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q8IW03 |
| Note | Gene ID: 283514; UniProt: Q8IW03; Chromosome: 13q14.13; Predicted MW: 30.7 kDa |
| Function | Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SIAH3 Polyclonal Antibody |
| Target | SIAH3 |
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