Rabbit Anti-RMD5A/RMND5A Polyclonal Antibody
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产品编号
PAV3412
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别名
required for meiotic nuclear division 5 homolog A, CTLH, GID2, GID2A, RMD5, p44CTLH
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | required for meiotic nuclear division 5 homolog A, CTLH, GID2, GID2A, RMD5, p44CTLH |
| Catalog Number | PAV3412 |
| Product Description | Rabbit polyclonal antibody raised against human RMND5A (E3 ubiquitin-protein transferase RMND5A). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | RMND5A |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Located in cytoplasm and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human RMND5A protein (UniProt: Q9H871) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 64795 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈44.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 44.0 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q9H871 |
| Note | Gene ID: 64795; UniProt: Q9H871; Chromosome: 2p11.2; Predicted MW: 44.0 kDa |
| Function | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human RMND5A Polyclonal Antibody |
| Target | RMND5A |
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