Rabbit Anti-PSMD5 Polyclonal Antibody
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产品编号
PAV3186
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别名
proteasome 26S subunit, non-ATPase 5, S5B
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | proteasome 26S subunit, non-ATPase 5, S5B |
| Catalog Number | PAV3186 |
| Product Description | Rabbit polyclonal antibody raised against human PSMD5 (26S proteasome non-ATPase regulatory subunit 5). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | PSMD5 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly. [provided by RefSeq, Jul 2012] |
| Immunogen | This antibody was raised against from part region of human PSMD5 protein (UniProt: Q16401) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 5711 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈56.2 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 56.2 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q16401 |
| Note | Gene ID: 5711; UniProt: Q16401; Chromosome: 9q33.2; Predicted MW: 56.2 kDa |
| Function | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human PSMD5 Polyclonal Antibody |
| Target | PSMD5 |
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