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Rabbit Anti-PSD13/PSMD13 Polyclonal Antibody
Rabbit Anti-PSD13/PSMD13 Polyclonal Antibody

Rabbit Anti-PSD13/PSMD13 Polyclonal Antibody

产品编号

PAV3179

别名

proteasome 26S subunit, non-ATPase 13, HSPC027, Rpn9, S11, p40.5

目录价格

InquiryRMB

规格
  • 100ul
产品介绍
Aliasproteasome 26S subunit, non-ATPase 13, HSPC027, Rpn9, S11, p40.5
Catalog NumberPAV3179
Product DescriptionRabbit polyclonal antibody raised against human PSMD13 (26S proteasome non-ATPase regulatory subunit 13). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular NamePSMD13
SpeciesHuman, Mouse, Rat
HostRabbit
Size100ul
ClonityPolyclonal
Protein Family自噬与泛素化
Concentration1 mg/ml
Purificationaffinity-chromatography
Formulationsupply in PBS containing 50% glycerol, and 0.02% sodium azide.
BackgroundThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
ImmunogenThis antibody was raised against from part region of human PSMD13 protein (UniProt: Q9UNM6)
ApplicationWB, ELISA
Recommended DilutionWB 1:500-2000 ELISA 1:5000-20000
Gene ID5719
TagUnconjugated
Cross-reactivityHuman, Mouse, Rat
Predicted Molecular Weight≈42.9 kDa
Storage ConditionStore at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping ConditionThis product is shipped on blue ice.
Molecular Weight42.9 kDa
Cross-reactivityHuman, Mouse, Rat
Uniprot IDQ9UNM6
NoteGene ID: 5719; UniProt: Q9UNM6; Chromosome: 11p15.5; Predicted MW: 42.9 kDa
FunctionComponent of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Product Declaration本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full NameRabbit Anti-Human PSMD13 Polyclonal Antibody
TargetPSMD13

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