Rabbit Anti-PJA1 Polyclonal Antibody

产品编号

PAV3050

别名

praja ring finger ubiquitin ligase 1, PRAJA1, RNF70

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	praja ring finger ubiquitin ligase 1, PRAJA1, RNF70
Catalog Number	PAV3050
Product Description	Rabbit polyclonal antibody raised against human PJA1 (E3 ubiquitin-protein ligase Praja-1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	PJA1
Species	Human
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	自噬与泛素化
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Immunogen	This antibody was raised against from part region of human PJA1 protein (UniProt: Q8NG27)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	64219
Tag	Unconjugated
Cross-reactivity	Human
Predicted Molecular Weight	≈71.0 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	71.0 kDa
Cross-reactivity	Human
Uniprot ID	Q8NG27
Note	Gene ID: 64219; UniProt: Q8NG27; Chromosome: Xq13.1; Predicted MW: 71.0 kDa
Function	Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human PJA1 Polyclonal Antibody
Target	PJA1