Rabbit Anti-MIB2 Polyclonal Antibody
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产品编号
PAV2308
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别名
MIB E3 ubiquitin protein ligase 2, ZZANK1, ZZZ5
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | MIB E3 ubiquitin protein ligase 2, ZZANK1, ZZZ5 |
| Catalog Number | PAV2308 |
| Product Description | Rabbit polyclonal antibody raised against human MIB2 (E3 ubiquitin-protein ligase MIB2). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | MIB2 |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 自噬与泛素化 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is an E3 ubiquitin protein ligase that mediates ubiquitination of proteins in the Notch signaling pathway. The encoded protein may be a suppressor of melanoma invasion. [provided by RefSeq, Mar 2017] |
| Immunogen | This antibody was raised against from part region of human MIB2 protein (UniProt: Q96AX9) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 142678 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈103.7 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 103.7 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q96AX9 |
| Note | Gene ID: 142678; UniProt: Q96AX9; Chromosome: 1p36.33; Predicted MW: 103.7 kDa |
| Function | E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human MIB2 Polyclonal Antibody |
| Target | MIB2 |
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