Rabbit Anti-TM2D1 Polyclonal Antibody

产品编号

PAV4064

别名

TM2 domain containing 1, BBP

目录价格

InquiryRMB

规格

100ul

DATASHEET COA

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产品介绍

Alias	TM2 domain containing 1, BBP
Catalog Number	PAV4064
Product Description	Rabbit polyclonal antibody raised against human TM2D1 (TM2 domain-containing protein 1). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml.
Molecular Name	TM2D1
Species	Human, Mouse
Host	Rabbit
Size	100ul
Clonity	Polyclonal
Protein Family	凋亡
Concentration	1 mg/ml
Purification	affinity-chromatography
Formulation	supply in PBS containing 50% glycerol, and 0.02% sodium azide.
Background	The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Immunogen	This antibody was raised against from part region of human TM2D1 protein (UniProt: Q9BX74)
Application	WB, ELISA
Recommended Dilution	WB 1:500-2000 ELISA 1:5000-20000
Gene ID	83941
Tag	Unconjugated
Cross-reactivity	Human, Mouse
Predicted Molecular Weight	≈22.3 kDa
Storage Condition	Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles.
Shipping Condition	This product is shipped on blue ice.
Molecular Weight	22.3 kDa
Cross-reactivity	Human, Mouse
Uniprot ID	Q9BX74
Note	Gene ID: 83941; UniProt: Q9BX74; Chromosome: 1p31.3; Predicted MW: 22.3 kDa
Function	May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42.
Product Declaration	本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。
Product Full Name	Rabbit Anti-Human TM2D1 Polyclonal Antibody
Target	TM2D1