Rabbit Anti-TRIP6 Polyclonal Antibody
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产品编号
PAV4133
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别名
thyroid hormone receptor interactor 6, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | thyroid hormone receptor interactor 6, OIP-1, OIP1, TRIP-6, TRIP6i2, ZRP-1 |
| Catalog Number | PAV4133 |
| Product Description | Rabbit polyclonal antibody raised against human TRIP6 (Thyroid receptor-interacting protein 6). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | TRIP6 |
| Species | Human |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他信号分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | This antibody was raised against from part region of human TRIP6 protein (UniProt: Q15654) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 7205 |
| Tag | Unconjugated |
| Cross-reactivity | Human |
| Predicted Molecular Weight | ≈50.3 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 50.3 kDa |
| Cross-reactivity | Human |
| Uniprot ID | Q15654 |
| Note | Gene ID: 7205; UniProt: Q15654; Chromosome: 7q22.1; Predicted MW: 50.3 kDa |
| Function | Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human TRIP6 Polyclonal Antibody |
| Target | TRIP6 |
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