Rabbit Anti-STAC3 Polyclonal Antibody
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产品编号
PAV3843
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别名
SH3 and cysteine rich domain 3, CMYO13, CMYP13, MYPBB, NAM
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | SH3 and cysteine rich domain 3, CMYO13, CMYP13, MYPBB, NAM |
| Catalog Number | PAV3843 |
| Product Description | Rabbit polyclonal antibody raised against human STAC3 (SH3 and cysteine-rich domain-containing protein 3). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB, ELISA. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | STAC3 |
| Species | Human, Mouse |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他信号分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | The protein encoded by this gene is a component of the excitation-contraction coupling machinery of muscles. This protein is a member of the Stac gene family and contains an N-terminal cysteine-rich domain and two SH3 domains. Mutations in this gene are a cause of Native American myopathy. [provided by RefSeq, Nov 2013] |
| Immunogen | This antibody was raised against from part region of human STAC3 protein (UniProt: Q96MF2) |
| Application | WB, ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Gene ID | 246329 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Predicted Molecular Weight | ≈41.5 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 41.5 kDa |
| Cross-reactivity | Human, Mouse |
| Uniprot ID | Q96MF2 |
| Note | Gene ID: 246329; UniProt: Q96MF2; Chromosome: 12q13.3; Predicted MW: 41.5 kDa |
| Function | Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity). Slows down the inactivation rate of the calcium channel CACNA1C. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human STAC3 Polyclonal Antibody |
| Target | STAC3 |
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