Rabbit Anti-SARAF Polyclonal Antibody
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产品编号
PAV3574
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别名
store-operated calcium entry associated regulatory factor, FOAP-7, HSPC035, TMEM66, XTP3
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目录价格
InquiryRMB
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规格
- 100ul
产品介绍
| Alias | store-operated calcium entry associated regulatory factor, FOAP-7, HSPC035, TMEM66, XTP3 |
| Catalog Number | PAV3574 |
| Product Description | Rabbit polyclonal antibody raised against human SARAF (Store-operated calcium entry-associated regulatory factor). Affinity purified from rabbit antiserum by antigen-specific affinity chromatography. Validated applications: WB. Supplied as liquid in PBS containing 50% glycerol and 0.02% sodium azide at 1 mg/ml. |
| Molecular Name | SARAF |
| Species | Human, Mouse, Rat |
| Host | Rabbit |
| Size | 100ul |
| Clonity | Polyclonal |
| Protein Family | 其他信号分子 |
| Concentration | 1 mg/ml |
| Purification | affinity-chromatography |
| Formulation | supply in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Background | Involved in regulation of store-operated calcium entry. Located in endoplasmic reticulum membrane and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Jul 2025] |
| Immunogen | This antibody was raised against from part region of human SARAF protein (UniProt: Q96BY9) |
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Gene ID | 51669 |
| Tag | Unconjugated |
| Cross-reactivity | Human, Mouse, Rat |
| Predicted Molecular Weight | ≈37.0 kDa |
| Storage Condition | Store at 4℃ for for short term storage. It is recommended to aliquote to ~10ul per vial and store at -20℃ for long term storage. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | This product is shipped on blue ice. |
| Molecular Weight | 37.0 kDa |
| Cross-reactivity | Human, Mouse, Rat |
| Uniprot ID | Q96BY9 |
| Note | Gene ID: 51669; UniProt: Q96BY9; Chromosome: 8p12; Predicted MW: 37.0 kDa |
| Function | Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions. |
| Product Declaration | 本产品仅用于研究用途(RUO)。不能用于诊断或直接用于人体实验。 |
| Product Full Name | Rabbit Anti-Human SARAF Polyclonal Antibody |
| Target | SARAF |
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