牛结核ESAT-6:CFP-10融合抗原
-
产品编号
ANAG1149
-
别名
BTB Ag; BTB antigen
-
规格
- 1mg
| Catalog Number | ANAG1149 |
| Alias | BTB Ag; BTB antigen |
| Size | 1mg |
| Product Description | 牛结核ESAT-6:CFP-10融合抗原(ANAG1149)是通过原核系统表达得到的重组抗原,该蛋白可用于检测抗原抗体的免疫反应。 |
| Molecular Name | BTB |
| Product Introduction | BTB:牛结核病,是由牛分枝杆菌引起的一种重要的人畜共患慢性传染病。 |
| Species | 牛结核杆菌ESAT-6:CFP-10融合 |
| Host | E.coli |
| Purity | > 85% as determined by Tris-Bis PAGE |
| Purification | Affinity purification chromatography |
| Storage Condition | The lyophilized protein can be stored at -20 °C.After re-solubilization, the protein can be stored at -20°C to 40°C for one month without detectable loss of activity. The protein product is stable for 12 months from the date of receipt when stored at -80°C. |
| Formulation | PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Shipping Condition | In general, liquid samples are shipped on dry ice and lyophilised samples are shipped on blue ice. |
| Background | In immunology, an antigen (Ag) is a molecule or molecular structure that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. |
| Application | For the development of immunological kits such as colloidal gold, elisa, or for serological research |
| Product Declaration | 该产品仅供科研使用,不可直接用于人体或注射。 |
融合抗原是通过基因工程技术将两种或多种不同蛋白(或蛋白片段)的基因连接在一起,表达出的一个单一多肽链。主要用途一:提高检测灵敏度与覆盖面。例如,将猪蓝耳病病毒的N蛋白和NSP7蛋白融合,一个试剂就能同时检测针对这两种蛋白的抗体,扩大了检测的“窗口期”,提高了发现早期感染或既往感染动物的能力。主要用途二:作为诊断标志物。最经典的例子是伪狂犬病的gE-gI融合抗原。由于疫苗是gE/gI基因缺失的,自然感染动物才会产生针对此融合蛋白的抗体,从而用于区分感染与免疫动物。
0