Mouse CD137L Protein, His Tag_天津卡梅德科技发展有限公司

>>

>>

>>

>

Mouse CD137L Protein, His Tag

Mouse CD137L Protein, His Tag

产品编号

KMP2316

别名

肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9

规格

50ug
100ug
200ug

DATASHEET MSDS

立即询价加入询价列表大包装定制

产品介绍

Alias	肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9
Catalog Number	KMP2316
Product Description	The Mouse CD137L Protein(KMP2316) is produced in HEK293 Cells and the target gene encoding Arg104-Glu309 is expressed with a 10His tag at the N-terminus.
Molecular Name	CD137L
Species	Mouse
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Tumor necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumor necrosis factor family. Mouse 4-1BBL cDNA encodes a 309 amino acid residues(aa) protein with an 82 aa N-terminal cytoplasmic domain, a 21 aa transmembrane domain and a 206 aa C-terminal extracellular domain. The extracellular domain of 4-1BBL has a tertiary structure similar to that of other TNFSF members, but shares only low aa sequence homology(14-16%). 4-1BBL is predominantly expressed on activated antigen presenting cells(APCs) such as B cells, macrophages and dendritic cells(DCs). It is also expressed on most T and B lymphoma cell lines. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
SDS-PAGE
Predicted Molecular Weight	22.97 kDa
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
Uniprot ID	P41274
Function	Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

推荐产品

400-621-6806
614353794
周一至周五 9:00-18:00
0