Mouse CD68 Protein, His Tag_天津卡梅德科技发展有限公司

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Mouse CD68 Protein, His Tag

Mouse CD68 Protein, His Tag

产品编号

KMP3957

别名

清道夫受体D类成员1, CD68 Protein, Mouse CD68 Protein, His Tag

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	清道夫受体D类成员1, CD68 Protein, Mouse CD68 Protein, His Tag
Catalog Number	KMP3957
Product Description	The Mouse CD68 Protein(KMP3957) is produced in Insect Cells. A DNA sequence encoding the Mouse CD68 (NP_001277987.1) (Met1-Ser291) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CD68
Species	Mouse
Host	Insect Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	20mM Tris, 150mM NaCl, 10% Glycerol, pH8.0
Background	Macrosialin, also known as CD68 and Gp11, is a single-pass type I membrane protein which belongs to theLAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	30.2 kDa

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